Photo of Weihua Guan

Weihua Guan

Associate Professor

Affiliation(s):

  • School of Electrical Engineering and Computer Science
  • Electrical Engineering
  • Biomedical Engineering

228 Electrical Engineering West

wzg111@psu.edu

814-867-5748

Personal or Departmental Website

Research Areas:

Biomedical Devices; Electronic Materials and Devices; Optical Materials, Devices, and Systems

Interest Areas:

Electro-fluidic and opto-fluidic devices and systems for biosensing and actuation, bioMEMS/NEMS, Lab-on-a-chip, Micro/Nanofluidics, Electrokinetic Phenomena, Point-of-care Testing.

 
 

 

Education

  • Ph D, Electrical Engineering, Yale University, 2013

Publications

Journal Articles

  • Ming Dong, Aneesh Kshirsagar, Anthony J Politza and Weihua Guan, 2024, "High Fidelity Machine-Learning-Assisted False Positive Discrimination in Loop-Mediated Isothermal Amplification Using Nanopore-Based Sizing and Counting", ACS Nano
  • Md Ahasan Ahamed, Muhammad Khalid, Ming Dong, Anthony J Politza, Zhikun Zhang, Aneesh Kshirsagar, Tianyi Liu and Weihua Guan, 2024, "Sensitive and specific CRISPR-Cas12a assisted nanopore with RPA for Monkeypox detection", Biosensors and Bioelectronics, 246, pp. 115866
  • Anthony J Politza, Reza Nouri and Weihua Guan, 2023, "Digital CRISPR systems for the next generation of nucleic acid quantification", TrAC Trends in Analytical Chemistry, pp. 116917
  • Wenchang Zhang, Ya Li, Bing Chen, Yuan Zhang, Ziqiang Du, Feibin Xiang, Yu Hu, Xiaochen Meng, Chunliang Shang, Shengfa Liang and Weihua Guan, 2023, "Fully integrated point-of-care blood cell count using multi-frame morphology analysis", Biosensors and Bioelectronics, 223, pp. 115012
  • Aneesh Kshirsagar, Gihoon Choi, Vishaka Santosh, Tara Harvey, Robert Cory Bernhards and Weihua Guan, 2023, "Handheld Purification-Free Nucleic Acid Testing Device for Point-of-Need Detection of Malaria from Whole Blood", ACS sensors
  • Laurie Calvet, Weihua Guan, James Klemic, Takhee Lee, Mohsen Nami, Jeffrey Sleight, Eric Stern, Shari Yosinski and Chongwu Zhou, 2023, "Editorial for 'focus collection in memory of Prof Mark A Reed'", Nanotechnology, 35, (11), pp. 110201
  • Tianyi Liu, Anthony J Politza, Aneesh Kshirsagar, Yusheng Zhu and Weihua Guan, 2023, "Compact Point-of-Care Device for Self-Administered HIV Viral Load Tests from Whole Blood", ACS sensors, 8, (12), pp. 4716--4727
  • Ming Dong, Zifan Tang and Weihua Guan, 2023, "Ensuring fair assessment of solid-state nanopore sensors with reporting baseline current", Applied Physics Letters, 123, (15)
  • Ming Dong, Reza Nouri, Zifan Tang and Weihua Guan, 2023, "Morphology around Nanopores Fabricated by Laser-Assisted Dielectric Breakdown and Its Impact on Ion and DNA Transport and Sensing", ACS Applied Materials & Interfaces
  • Weihua Guan, 2023, "Probing when dCas9 tolerates DNA mismatches", Nature Biomedical Engineering, pp. 1--2
  • Anthony J Politza, Tianyi Liu and Weihua Guan, 2023, "Programmable magnetic robot (ProMagBot) for automated nucleic acid extraction at the point of need", Lab on a Chip, 23, (17), pp. 3882--3892
  • Reza Nouri, Yuqian Jiang, Anthony J Politza, Tianyi Liu, Wallace H Greene, Yusheng Zhu, Jonathan Nunez, Xiaojun Lian and Weihua Guan, 2023, "STAMP-Based Digital CRISPR-Cas13a for Amplification-Free Quantification of HIV-1 Plasma Viral Loads", ACS nano, pp. 512138
  • Zifan Tang, Reza Nouri, Ming Dong, Jianbo Yang, Wallace H Greene, Yusheng Zhu, Michele Yon, Meera Surendran Nair, Suresh V. Kuchipudi and Weihua Guan, 2022, "Rapid detection of novel coronavirus SARS-CoV-2 by RT-LAMP coupled solid-state nanopores", Biosensors and Bioelectronics, 197, pp. 113759
  • Reza Nouri, Ming Dong, Anthony J Politza and Weihua Guan, 2022, "Figure of merit for CRISPR-based nucleic acid-sensing systems: Improvement strategies and performance comparison", ACS sensors, 7, (3), pp. 900--911
  • Tianyi Liu, Gihoon Choi, Zifan Tang, Aneesh Kshirsagar, Anthony J Politza and Weihua Guan, 2022, "Fingerpick Blood-Based Nucleic Acid Testing on A USB Interfaced Device towards HIV self-testing", Biosensors and Bioelectronics, 209, pp. 114255
  • Feibin Xiang, Ming Dong, Wenchang Zhang, Shengfa Liang and Weihua Guan, 2022, "Modeling pyramidal silicon nanopores with effective ion transport", Nanotechnology, 33, (48), pp. 485503
  • Ming Dong, Zifan Tang, Steven Hicks and Weihua Guan, 2022, "Rolling circle amplification-coupled glass nanopore counting of mild traumatic brain injury-related salivary miRNAs", Analytical Chemistry, 94, (9), pp. 3865--3871
  • Zifan Tang, Jiarui Cui, Aneesh Kshirsagar, Tianyi Liu, Michele Yon, Suresh V. Kuchipudi and Weihua Guan, 2022, "SLIDE: saliva-based SARS-CoV-2 self-testing with RT-LAMP in a mobile device", ACS sensors, 7, (8), pp. 2370--2378
  • Gihoon Choi, Zifan Tang and Weihua Guan, 2021, "Microfluidic high-throughput single-cell mechanotyping: Devices and applications", Nanotechnology and Precision Engineering, 4, (4), pp. 045002
  • Reza Nouri, Yuqian Jiang, Zifan Tang, Xiaojun Lance Lian and Weihua Guan, 2021, "Detection of SARS-CoV-2 with Solid-State CRISPR-Cas12a-Assisted Nanopores", Nano Letters, 21, (19), pp. 8393-8400
  • Reza Nouri, Zifan Tang, Ming Dong, Tianyi Liu, Aneesh Kshirsagar and Weihua Guan, 2021, "CRISPR-based detection of SARS-CoV-2: A review from sample to result", Biosensors and Bioelectronics, 178, pp. 113012
  • Zifan Tang, Ming Dong, Xiaodong He and Weihua Guan, 2021, "On Stochastic Reduction in Laser-Assisted Dielectric Breakdown for Programmable Nanopore Fabrication", ACS Applied Materials & Interfaces
  • Reza Nouri and Weihua Guan, 2021, "Nanofluidic Charged-Coupled Devices for Controlled DNA Transport and Separation.", Nanotechnology
  • Shengfa Liang, Feibin Xia, Zifan Tang, Reza Nouri, Xiaodong He, Ming Dong and Weihua Guan, 2020, "Noise in Nanopore Sensors: Sources, Models, Reduction And Benchmarking", Nanotechnology and Precision Engineering
  • Xiaodong He, Zifan Tang, Shengfa Liang, Ming Liu and Weihua Guan, 2020, "Confocal scanning photoluminescence for mapping electron and photon beam-induced microscopic changes in SiNx during nanopore fabrication", Nanotechnology, 31, (39)
  • Gihoon Choi, Reza Nouri, Lauren Zarzar and Weihua Guan, 2020, "Microfluidic deformability-activated sorting of single particles", Microsystems & Nanoengineering, 6, (1)
  • Reza Nouri, Yuqian Jiang, Xiaojun Lance Lian and Weihua Guan, 2020, "Sequence-Specific Recognition of HIV-1 DNA with Solid-State CRISPR-Cas12a-Assisted Nanopores (SCAN)", ACS Sensors, 5, (5), pp. 1273-1280
  • Weihua Guan, 2020, "Foreword to the special issue on micro/nano biosensors", Nanotechnology and Precision Engineering, (3), pp. 1
  • Ming Dong, Zifan Tang, Xiaodong He and Weihua Guan, 2020, "Direct Observation of Redox Induced Bubble Generation and Nanopore Formation Dynamics in Controlled Dielectric Breakdown", ACS Applied Electronic Materials
  • Reza Nouri, Zifan Tang and Weihua Guan, 2019, "Calibration-Free Nanopore Digital Counting of Single Molecules", Analytical Chemistry, 91, (17), pp. 10915-11488
  • Wenchang Zhang, Yuan Hu, Gihoon Choi, Shengfa Liang, Ming Liu and Weihua Guan, 2019, "Microfluidic multiple cross-correlated Coulter counter for improved particle size analysis", Sensors and Actuators B: Chemical, 296, pp. 126615
  • Gihoon Choi, Erica Murphy and Weihua Guan, 2019, "Microfluidic Time-Division Multiplexing Accessing Resistive Pulse Sensor for Particle Analysis", ACS Sensors, 4, (7), pp. 1957-1963
  • Kamyar Akbari Roshan, Zifan Tang and Weihua Guan, 2019, "High fidelity moving Z-score based controlled breakdown fabrication of solid-state nanopore", Nanotechnology, 30, pp. 095502
  • Zifan Tang, Gihoon Choi, Reza Nouri and Weihua Guan, 2019, "Loop-Mediated Isothermal Amplification-Coupled Glass Nanopore Counting Toward Sensitive and Specific Nucleic Acid Testing", NANO LETTERS, 19, (11), pp. 7927-7934
  • Reza Nouri, Zifan Tang and Weihua Guan, 2019, "Quantitative Analysis of Factors Affecting the Event Rate in Glass Nanopore Sensors", ACS SENSORS, 4, (11), pp. 3007-3013
  • Gihoon Choi, Theodore Prince, Jun Miao, Liwang Cui and Weihua Guan, 2018, "Sample-to-answer palm-sized nucleic acid testing device towards low-cost malaria mass screening", Biosensors and Bioelectronics, 115, pp. 83-90
  • Taehwan Kim, Jared S. Price, Alex Grede, Sora Lee, Gihoon Choi, Weihua Guan, Thomas N Jackson and Noel Giebink, 2018, "Kirigami-Inspired 3D Organic Light-Emitting Diode (OLED) Lighting Concepts", Advanced Materials Technologies, 3, (7), pp. 1800067
  • Xiaonan Yang, Zhuofa Chen, Jun Miao, Liwang Cui and Weihua Guan, 2017, "High-throughput and label-free parasitemia quantification and stage differentiation for malaria-infected red blood cells", Biosensors and Bioelectronics, 98, pp. 408-414
  • Gihoon Choi, Daniel Song, Sony Shrestha, Jun Miao, Liwang Cui and Weihua Guan, 2016, "A field-deployable mobile molecular diagnostic system for malaria at the point of need", Lab on a Chip, 16, (22), pp. 4341–4349
  • Zhuofa Chen, Weizhi Li, Gihoon Choi, Xiaonan Yang, Jun Miao, Liwang Cui and Weihua Guan, 2016, "Arbitrarily Accessible 3D Microfluidic Device for Combinatorial High-Throughput Drug Screening", Sensors, 16, (10), pp. 1616
  • Sylvia Xin Li, Weihua Guan, Benjamin Weiner and Mark A Reed, 2015, "Direct observation of charge inversion in divalent nanofluidic devices", Nano Letters, 15, (8), pp. 5046–5051
  • Weihua Guan, Liben Chen, Tushar D Rane and Tza-Huei Wang, 2015, "Droplet Digital Enzyme-Linked Oligonucleotide Hybridization Assay for Absolute RNA Quantification", Scientific Reports, 5, pp. 13795
  • Weihua Guan, Xuexin Duan and Mark A Reed, 2014, "Highly specific and sensitive non-enzymatic determination of uric acid in serum and urine by extended gate field effect transistor sensors", Biosensors and Bioelectronics, 51, pp. 225–231
  • Weihua Guan, Sylvia Xin Li and Mark A Reed, 2014, "Voltage gated ion and molecule transport in engineered nanochannels: theory, fabrication and applications", Nanotechnology, 25, (12), pp. 122001
  • Weihua Guan, Nitin K Rajan, Xuexin Duan and Mark A Reed, 2013, "Quantitative probing of surface charges at dielectric–electrolyte interfaces", Lab on a Chip, 13, (7), pp. 1431–1436
  • Weihua Guan and Mark A Reed, 2012, "Electric field modulation of the membrane potential in solid-state ion channels", Nano Letters, 12, (12), pp. 6441–6447
  • Jae Hyun Park, Weihua Guan, Mark A Reed and Predrag S Krstic, 2012, "Tunable aqueous virtual micropore", Small, 8, (6), pp. 907–912
  • Weihua Guan, Rong Fan and Mark A Reed, 2011, "Field-effect reconfigurable nanofluidic ionic diodes", Nature Communications, 2, pp. 506
  • Weihua Guan, Jae Hyun Park, Predrag S Krstic and Mark A Reed, 2011, "Non-vanishing ponderomotive AC electrophoretic effect for particle trapping", Nanotechnology, 22, (24), pp. 245103
  • Weihua Guan, Sony Joseph, Jae Hyun Park, Predrag S Krstic and Mark A Reed, 2011, "Paul trapping of charged particles in aqueous solution", Proceedings of the National Academy of Sciences, 108, (23), pp. 9326–9330
  • Sony Joseph, Weihua Guan, Mark A Reed and Predrag S Krstic, 2010, "A long DNA segment in a linear nanoscale Paul trap", Nanotechnology, 21, (1), pp. 015103
  • Ming Liu, Z Abid, Wei Wang, Xiaoli He, Qi Liu and Weihua Guan, 2009, "Multilevel resistive switching with ionic and metallic filaments", Applied Physics Letters, 94, (23), pp. 233106
  • Weihua Guan, Shibing Long, Yuan Hu, Qi Liu, Qin Wang and Ming Liu, 2009, "Resistance switching characteristics of zirconium oxide containing gold nanocrystals for nonvolatile memory applications", Journal of nanoscience and nanotechnology, 9, (2), pp. 723–726
  • Sen Zhang, Shibing Long, Weihua Guan, Qi Liu, Qin Wang and Ming Liu, 2009, "Resistive switching characteristics of MnOx-based ReRAM", Journal of Physics D: Applied Physics, 42, (5), pp. 055112
  • Qi Liu, Shibing Long, Weihua Guan, Sen Zhang, Ming Liu and Chen Junning, 2009, "Unipolar resistive switching of Au+-implanted ZrO2 films", Journal of Semiconductors, 30, (4), pp. 042001
  • Zhigang Li, Weihua Guan, Ming Liu, Shibing Long, Rui Jia, Jin Lv, Yi Shi and Xinwei Zhao, 2008, "Charge storage characteristics of metal-induced nanocrystalline in erbium-doped amorphous silicon films", Thin Solid Films, 516, (21), pp. 7657–7660
  • Qin Wang, Rui Jia, Weihua Guan, Weilong Li, Qi Liu, Yuan Hu, Shibing Long, Baoqin Chen, Ming Liu, Tianchun Ye and others, 2008, "Comparison of discrete-storage nonvolatile memories: advantage of hybrid method for fabrication of Au nanocrystal nonvolatile memory", Journal of Physics D: Applied Physics, 41, (3), pp. 035109
  • Weihua Guan, Shibing Long, Qi Liu, Ming Liu and Wei Wang, 2008, "Nonpolar Nonvolatile Resistive Switching in Cu Doped", Electron Device Letters, IEEE, 29, (5), pp. 434–437
  • Weihua Guan, Ming Liu, Shibing Long, Qi Liu and Wei Wang, 2008, "On the resistive switching mechanisms of Cu/ZrO2: Cu/Pt", Applied Physics Letters, 93, (22), pp. 223506
  • Lijuan Zhen, Weihua Guan, Liwei Shang, Ming Liu and Ge Liu, 2008, "Organic thin-film transistor memory with gold nanocrystals embedded in polyimide gate dielectric", Journal of Physics D: Applied Physics, 41, (13), pp. 135111
  • Qi Liu, Weihua Guan, Shibing Long, Ming Liu, Sen Zhang, Qin Wang and Junning Chen, 2008, "Resistance switching of Au-implanted-ZrO2 film for nonvolatile memory application", Journal of Applied Physics, 104, (11), pp. 114514
  • Qi Liu, Weihua Guan, Shibing Long, Rui Jia, Ming Liu and Junning Chen, 2008, "Resistive switching memory effect of ZrO2 films with Zr+ implanted", Applied Physics Letters, 92, (1), pp. 12117–12117
  • Weihua Guan, Shibing Long, Ming Liu, Zhigang Li, Yuan Hu and Qi Liu, 2007, "Fabrication and charging characteristics of MOS capacitor structure with metal nanocrystals embedded in gate oxide", Journal of Physics D: Applied Physics, 40, (9), pp. 2754
  • Weihua Guan, Shibing Long, Ming Liu, Qi Liu, Yuan Hu, Zhigang Li and Rui Jia, 2007, "Modeling of retention characteristics for metal and semiconductor nanocrystal memories", Solid-State Electronics, 51, (5), pp. 806–811
  • Weihua Guan, Shibing Long, Rui Jia and Ming Liu, 2007, "Nonvolatile resistive switching memory utilizing gold nanocrystals embedded in zirconium oxide", Applied Physics Letters, 91, (6), pp. 62111–62111

Conference Proceedings

  • Reza Nouri, Yuqian Jiang, Anthony J Politza, Xiaojun Lance Lian and Weihua Guan, 2022, "Digital CRISPR-based quantification of HIV-1", IEEE Sensors, pp. 1--4
  • Anthony Politza, Tianyi Liu and Weihua Guan, 2022, "Programmable Magnetic Robot (ProMagBot) For Fully Automated Nucleic Acid Sample Preparation at The Point of Need", Hilton Head Workshop
  • Zifan Tang, Jiarui Cui, Aneesh Kshirsagar, Tianyi Liu and Weihua Guan, 2022, "Saliva-based SARS-Cov-2 Self-Testing with RT-LAMP In a Mobile Device (SLIDE)", Hilton Head Workshop
  • Zifan Tang, Jiarui Cui, Aneesh Kshirsagar, Tianyi Liu and Weihua Guan, 2022, "Live Demonstration: Saliva-based SARS-CoV-2 Self-Testing with RT-LAMP In a Mobile Device (Invited Paper)", IEEE Sensors, pp. 1--4
  • Anthony J Politza, Tianyi Liu and Weihua Guan, 2022, "Programmable Magnetic Robot (ProMagBot) for Automated Nucleic Acid Extraction at the Point of Need", Chemical and Biological Defense Science & Technology (CBD S&T) Conference
  • Reza Nouri, Yuqian Jiang, Anthony J Politza, Xiaojun Lian and Weihua Guan, 2022, "Amplification Free Digital CRISPR-Cas13a for Absolute Quantification of HIV-1 RNA", Chemical and Biological Defense Science & Technology (CBD S&T) Conference
  • Tianyi Liu, Aneesh Kshirsagar, Anthony J Politza and Weihua Guan, 2022, "Fingerpick Blood-Based HIV Self-Nucleic Acid Testing on USB At The Point of Need", Chemical and Biological Defense Science & Technology (CBD S&T) Conference
  • Aneesh Kshirsagar, Dean Derosa, Reza Nouri, Tianyi Liu and Weihua Guan, 2022, "iNAAT: A universal open-source mobile device for field deployable real-time isothermal nucleic acid amplification testing of Covid-19", Chemical and Biological Defense Science & Technology (CBD S&T) Conference
  • Reza Nouri, Yuqian Jiang, Zifan Tang, Xiaojun Lian and Weihua Guan, 2021, "Sequence-Specific Recognition of SARS COV-2 with Solid-State CRISPR-Cas12a-Assisted Nanopores (SCAN)", MicroTAS
  • Zifan Tang, Reza Nouri, Yusheng Zhu, Suresh Kuchipudi and Weihua Guan, 2021, "Rapid Detection of Novel Coronavirus Sars-CoV-2 by Solid-State Nanopore", MicroTAS
  • Ming Dong, Zifan Tang, Steve Hicks and Weihua Guan, 2021, "Rolling Circle Amplification-Coupled Nanopore for Quantification of miRNAs", MicroTAS
  • Zifan Tang, Xiaodong He and Weihua Guan, 2020, "Dynamics of Laser-Assisted Silicon Nitride Dielectric Breakdown for Deterministic Fabrication of Solid-State Nanopore", Biophysical Society Annual Meeting, Elsevier, 118, (3), pp. 159a
  • Kamyar Roshan and Weihua Guan, 2019, "False negative and false positive free nanopore fabrication via adaptive learning of the controlled dielectric breakdown", Transducers
  • Gihoon Choi and Weihua Guan, 2019, "Non-centrifugal microfluidic nucleic acid testing on lab-on-a-disc", Transducers
  • Kamyar Akbari Roshan and Weihua Guan, 2019, "Optically Assisted Localization of Solid-State Nanopore during Controlled Breakdown Fabrication", Biophysical Society Annual Meeting, 116, (3), pp. 293A-293A
  • Zifan Tang and Weihua Guan, 2019, "Real-Time Nanopore Couting of Amplicons for Ultrasensitive and Lable-Free Sequence-Specific DNA Detection", Biophysical Society Annual Meeting, 116, (3), pp. 149A-149A
  • Reza Nouri, Zifan Tang and Weihua Guan, 2019, "Calibration-Free Nanopore Digital Counting of Single Molecules", BMES Annual Meeting
  • Gihoon Choi, Reza No andri, , 2019, "Microfluidic Deformability-activated Cell Sorting (DACS)", BMES Annual Meeting
  • Gihoon Choi and Weihua Guan, 2019, "Live Demonstration: Sample-to-Answer Nucleic Acid Testing Device for Point-of-Care Applications", IEEE Sensor
  • Gihoon Choi, Erica Murphy and Weihua Guan, 2019, "Time-division multiplexed resistive pulse sensor on a microfluidic chip", IEEE Sensor
  • Reza Nouri, Zifan Tang and Weihua Guan, 2019, "Calibration-Free Electrical Quantification of Single Molecules Using Nanopore Digital Counting", IEEE Sensor
  • Gihoon Choi and Weihua Guan, 2019, "Live Demonstration of AnyMDx: a Handheld All-in-One NAAT Device", HI-POCT
  • Zifan Tang, Gihoon Choi, Reza Nouri and Weihua Guan, 2019, "Nanopore Digital Counting of Amplicons for Ultrasensitive Electronic DNA Detection", IEEE International Electron Devices Meeting (IEDM)
  • Zifan Tang, Reza Nouri, Gihoon Choi and Weihua Guan, 2019, "Digital Nanopore For Single Molecule Quantification: Pathway Towards Noise-Robustness, Ultra Sensitivity, Selectivity and Fast Response", IEEE SISC
  • Gihoon Choi, Theodore Prince, Jun Miao, Liwang Cui and Weihua Guan, 2017, "Portable sample-to-answer multiplexed molecular diagnosis for malaria in remote areas", MicroTAS
  • Gihoon Choi, Theodore Prince, Jun Miao, Liwang Cui and Weihua Guan, 2017, "Point Of Care Nucleic Acid Testing For Highly Sensitive Genus- And Species- Specific Detection of Malaria", HI-POCT
  • Gihoon Choi, Daniel Song, Jun Miao, Liwang Cui and Weihua Guan, 2017, "Sample-to-answer mobile malaria molecular diagnostic system for resource-limiting areas", IEEE MEMS
  • Xiaonan Yang, Zhuofa Chen, Gihoon Choi, Jun Miao, Liwang Cui and Weihua Guan, 2017, "High-throughput and label-free parasitemia quantification and stage determination for plasmodium falciparum-infected red blood cells", IEEE MEMS
  • Gihoon Choi, Daniel Song, Jun Miao, Liwang Cui and Weihua Guan, 2016, "Mobile all-in-one malaria molecular diagnosis for field deployment in resource-limited areas", HI-POCT
  • Weihua Guan, 2016, "Drop-n-Go Malaria Molecular Diagnosis", Biodefense World Summit
  • Weihua Guan, 2016, "Microfluidic Combinatory Chip for High-Throughput Drug Screening", Biodefense World Summit
  • Weihua Guan, Liben Chen, Tushar Rane, Aniruddha Kaushik and Jeff Tza-Huei Wang, 2015, "Digital droplet ELOHA for nucleic acid molecule counting and analysis", Transducers, pp. 460–463
  • Weihua Guan, Rong Fan and Mark A Reed, 2013, "Field Effect Ionics In Nanochannels", Connecticut Microelectronics and Optoelectronics Symposium
  • Weihua Guan, Rong Fan and Mark A Reed, 2012, "Fabrication and characterization of field effect reconfigurable nanofluidic ionic diodes: Towards digitally-programmed manipulation of biomolecules", Device Research Conference
  • Weihua Guan, Rong Fan and Mark A Reed, 2012, "Solid-state Nanofluidic Ion Channels", Gordon Research Conference-Nanostructure Fabrication
  • Weihua Guan, Rong Fan and Mark A Reed, 2012, "Fabrication and Characterization of Field Effect Reconfigurable Nanofluidic Ionic Diodes: Building Blocks Towards Digitally-Programmed Manipulation of Biomolecules", International Conference on Electron, Ion, and Photon Beam Technology and Nanofabrication
  • Predrag Krstic, Mark Reed, Weihua Guan and J.H. Park, 2011, "DNA Transport and Sequencing Through a Quadrupole Gate", NHGRI DNA Sequencing Technology Development Grantee Meeting
  • Weihua Guan, JaeHyun Park, Predrag Krstic and Mark Reed, 2011, "AC electrophoretic effect in inhomogeneous electrical field: potentials for single molecule trapping", APS March Meeting
  • Weihua Guan, Mark Reed, Sony Joseph and Predrag Krstic, 2010, "Suppression of Brownian motion by electrodynamic confinement in aqueous solution", APS March Meeting
  • Ming Liu, Qi Liu, Shibing Long and Weihua Guan, 2010, "Formation and annihilation of Cu conductive filament in the nonpolar resistive switching Cu/ZrO 2: Cu/Pt ReRAM", IEEE International Symposium on Circuits and Systems
  • Predrag Krstic, Mark Reed, Weihua Guan and J.H. Park, 2010, "DNA Transport and Sequencing Through a Quadrupole Gate", NHGRI DNA Sequencing Technology Development Grantee Meeting
  • R Munden, A Vacic, E Castiglione, Weihua Guan, C Broadbridge and Mark Reed, 2009, "Aligned Gallium Nitride Nanowire Growth by Chemical Beam Epitaxy Method", APS March Meeting
  • Predrag Krstic, Mark Reed, Sony Joseph and Weihua Guan, 2009, "DNA Transport and Sequencing Through a Quadrupole Gate", NHGRI DNA Sequencing Technology Development Grantee Meeting
  • Ming Liu, Weihua Guan, Shibing Long, Qi Liu and Wei Wang, 2008, "Excellent resistive switching characteristics of Cu doped ZrO 2 and its 64 bit cross-point integration", IEEE International Conference on Solid-State and Integrated Circuit Technology, pp. 905–908
  • Weihua Guan, Shibing Long, Ming Liu and Wei Wang, 2008, "Nonvolatile resistive switching characteristics of HfO 2 with Cu doping", MRS Spring Meeting, Cambridge University Press, 1071, pp. 1071–F07
  • Weihua Guan, Ming Liu, Z Li, Y Hu, S Long and R Jia, 2008, "Simulation, Fabrication and Characteristics of Nanocrystal Non-Volatile Memories", IEEE International Nanoelectronics Conference
  • Q Wang, R Jia, WL Li, Weihua Guan, Q Liu, Y Hu, SB Long, BQ Chen, M Liu, TC Ye and others, 2007, "A hybrid method for fabrication of Au nanocrystals nonvolatile memory", IEEE Conference on Nanotechnology, pp. 938–941
  • Weihua Guan, Shibing Long, Rui Jia, Qi Liu, Yuan Hu, Qin Wang and Ming Liu, 2007, "Analysis of Charge Retention Characteristics for Metal and Semiconductor Nanocrystal Non-volatile Memories", IEEE International Conference on Electron Devices and Solid-State Circuits, pp. 141–144
  • W Guan, Z Li, Y Hu, SB Long and R Jia, 2007, "Nanocrystal Non-Volatile Memories: Simulation, Fabrication and Characteristics", International Conference on Micro- and Nano-Engineering, pp. 938–941

Abstracts

  • Md Ahasan Ahamed and Weihua Guan, 2024, "CRISPR-assisted solid-state nanopore sensor for rapid and sensitive point-of-care amendable of monkeypox virus detection via RPA amplification", Biophysical Journal, 123, (3), pp. 145a
  • Muhammad Khalid and Weihua Guan, 2024, "Size counting analysis of short nucleic acid molecules using high-resolution hydrogel-interfaced glass nanopore", Biophysical Journal, 123, (3), pp. 292a
  • Ming Dong and Weihua Guan, 2024, "Solid-state nanopore-sized counting for lamp false positive differentiation", Biophysical Journal, 123, (3), pp. 144a--145a

Research Projects

Honors and Awards

Service

Service to Penn State:

Service to External Organizations: