Photo of Sri-Rajasekhar (Raj) Kothapalli

Sri-Rajasekhar (Raj) Kothapalli

Associate Professor of Biomedical Engineering


  • Biomedical Engineering
  • Center for Acoustics and Vibration
  • Acoustics

325 Chemical and Biomedical Engineering Building


Personal or Departmental Website




  • BS, Math, Physics, Chemistry, Nagarjuna University, 1995
  • MS, Nuclear Physics, Andhra University, 1997
  • M Phil, Condensed Matter Physics, University of Hyderabad, 1998
  • M.Eng, Applied Optics, I.I.T Delhi, 2000
  • MS, Applied Physics, University of Massachusetts, Boston, 2004
  • Ph D, Biomedical Engineering, Washington University in St. Louis, 2009
  • Postdoctoral, Radiology, Stanford University, 2013



Journal Articles

  • Christopher Cheng and Sri-Rajasekhar Kothapalli, 2022, "Improving PMUT Receive Sensitivity via DC Bias and Piezoelectric Composition", Sensors, 22, (15)
  • Haoyang Chen and Sri-Rajasekhar Kothapalli, 2022, "A Transparent Ultrasound Array for Real-Time Optical, Ultrasound, and Photoacoustic Imaging", AAAS BME Frontiers, 2022
  • Shubham Mirg and Sri-Rajasekhar Kothapalli, 2022, "Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window"
  • Sumit Agrawal and Sri-Rajasekhar Kothapalli, 2021, "Modeling Combined Ultrasound and Photoacoustic Imaging: Simulations aiding Device Development and Deep Learning", Photoacoustics, 24, pp. 100304
  • Haoyang Chen and Sri-Rajasekhar Kothapalli, 2021, "A High Sensitivity Transparent Ultrasound Transducer Based on PMN-PT for Ultrasound and Photoacoustic Imaging", IEEE Sensors Letters, 5, (11), pp. 1-4
  • Haoyang Chen and Sri-Rajasekhar Kothapalli, 2021, "A transparent low intensity pulsed ultrasound (LIPUS) chip for high-throughput cell stimulation", Lab on a Chip, 21, (24), pp. 4734-4742
  • Amirsaeed Yazdani and Sri-Rajasekhar Kothapalli, 2021, "Simultaneous Denoising and Localization Network for Photoacoustic Target Localization", IEEE Transactions on Medical Imaging, 40, (9), pp. 2367-2379
  • Ajay Dangi and Sri-Rajasekhar Kothapalli, 2019, "A Photoacoustic Imaging Device using Piezoelectric Micromachined Ultrasound Transducers (PMUTs)", IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

Conference Proceedings


Research Projects

  • September 2022 - August 2025, "Dual-modality Ultrasound and Photoacoustic Molecular Imaging Strategies for Lethal Prostate Cancer Detection," (Sponsor: Congressionally Directed Medical Research Programs).
  • September 2020 - February 2024, "A portable photoacoustic imager for diagnosing vascular diseases," (Sponsor: National Institute of Biomedical Imaging and Bioengineering).

Honors and Awards

  • NSF CAREER, National Science Foundation, March 2023 - February 2028
  • NIH Pathway to Indepedence Grant Award K99/R00, National Institute of Health, May 2014 - June 2021
  • 2022 IEEE Sensors Letters Best Paper Award Runner-Up, IEEE Sensors Council, November 2022


Service to Penn State:

Service to External Organizations: